| 23 Feb 18 | Deportivo | 21:00 | RCD Español |
| 24 Feb 18 | Celta de Vigo | 13:00 | Eibar |
| 24 Feb 18 | Real Madrid | 16:15 | Alavés |
| 24 Feb 18 | Leganés | 18:30 | UD Las Palmas |
| 24 Feb 18 | Barcelona | 20:45 | Girona |
| 25 Feb 18 | Villarreal | 12:00 | Getafe |
| 25 Feb 18 | Ath. Bilbao | 16:15 | Málaga |
| 25 Feb 18 | Valencia cf | 18:30 | Real Sociedad |
| 25 Feb 18 | Sevilla | 20:45 | Atlético de Madrid |
| 26 Feb 18 | Levante | 21:00 | Betis |