| 16 Feb 18 | Girona | 3-0 | Leganés |
| 17 Feb 18 | Las Palmas | 1-2 | Sevilla |
| 17 Feb 18 | Eibar | 0-2 | Barcelona |
| 17 Feb 18 | Alaés | 1-0 | Deportivo |
| 17 Feb 18 | Málaga | 1-2 | Valencia |
| 18 Feb 18 | Real Sociedad | 3-0 | Levante |
| 18 Feb 18 | Atlético de Madrid | 2-0 | Ath. Bilbao |
| 18 Feb 18 | Español | 1-1 | Villarreal |
| 18 Feb 18 | Betis | 3-5 | Real Madrid |
| 19 Feb 18 | Getafe | 3-0 | Celta de vigo |